Nutrition, Metabolism & Genomics Group
 Nutrigenomics Lab
(Head: Prof. Dr. Michael Müller)

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MSc Course Nutritional Genomics and Genetics (HNE-34804) March - April 2012

The lectures are in room C8 (Tuesday and Wednesday and Thursday)

Date

Time

Location

Lecture

Activity

Lecturer

 

 

 

 

Week 1 (Why Nutrigenomics? What is the problem?)

 

Mon 12-03

13.30-17.15

PC612

 

eLearning Case I/1 (Intro)

Rusli/Hooiveld

Tue 13-03

14.30-16.15

C8

NGG1

Concept & Objectives of the Course; What are the nutritional challenges today? Nutrient-based and food-based approaches

Hooiveld

Wed 14-03

15.30-18.00

C8

NGG2

Overview / What is Nutrigenomics & molecular nutrition research?

Müller

Thu 15-03

14.30-16.15

C8

NGG3

Personal Genomes & Personal Health – the challenges

Müller

Fri 16-03

13.30-17.15

PC612

 

Paper assignments / questions & answers

Lange/Schwarz

 

 

 

 

Week 2 (What are the tools?)

 

Mon 19-03

13.30-17.15

PC612

 

eLearning Case I/2

Rusli

Tue 20-03

14.30-16.15

C8

NGG4

Genomics & Transcriptomics – Applications in Nutrigenomics

Boekschoten

Wed 21-03

15.30-18.00

C8

NGG5

Applications of animal model systems in nutrigenomics studies
What is the relevance of animal models for human nutrition research?

Hooiveld

Thu 22-03

14.30-16.15

C8

NGG6

Comprehensive phenotyping applications in Nutrigenomics

Müller

Fri 23-03

13.30-17.15

PC612

 

Paper assignments

Lange/Schwarz

 

 

 

 

Week 3 (From Genotype to Phenotype)

 

Mon 26-03

13.30-17.15

PC612

 

eLearning Case II

Rusli

Tue 27-03

14.30-16.15

C8

NGG7

Nutrition, Genetics and Sensitizing Genotypes

Müller

Wed 28-03

15.30-18.00

C8

NGG8

Complex diseases: GWAS From Genotype to Phenotype

Müller

Thu 29-03

14.30-16.15

C8

NGG9

Nutritional epigenetics and epigenomics

Steegenga

Fri 30-03

13.30-17.15

PC612

 

Paper assignments

Lange/Schwarz

 

 

 

 

Week 4 (From health to development of diseases)

 

Mon 02-04

13.30-17.15

PC612

 

eLearning Case III

Rusli

Tue 03-04

14.30-16.15

C8

NGG10

Nutrigenomics & Physiology / Role of liver & adipose tissue
Organ interaction and crosstalk

Müller

Wed 04-04

15.30-18.00

C8

NGG11

The role of the intestine as gatekeeper: Host, microbes, foods

Müller

Thu 05-04

14.30-16.15

C8

NGG12

Nutrigenomics of inflammation
The role of inflammation in the pathophysiology of complex diseases

Müller

Fri 06-04

 

 

 

GOOD FRIDAY

 

 

 

 

 

Week 5 (Practical Dry Lab) Group A: How to analyze a nutrigenomics data set

 

Mon 09-04

 

 

 

EASTERN MONDAY

 

Tue 10-04

13.30-17.15

PC22

 

The Nutrigenomics Data Set

Boekschoten/Esser

Wed 11-04

13.30-17.15

PC22

 

The Analysis

Boekschoten/Esser

Thu 12-04

13.30-17.15

PC22

 

Data Mining 1

Boekschoten/Esser

Fri 13-04

13.30-17.15

PC22

 

Data Mining 2 / Pathway Reconstruction

Boekschoten/Esser

 

 

 

 

Week 5 (Practical Wet Lab) Group B: How to perform a nutrigenomics experiment

 

Mon 09-04

 

 

 

EASTERN MONDAY

 

Tue 10-04

13.30-17.15

P57

 

Introduction practical course / Tissue culture (in groups)

Haenen/Lange

Wed 11-04

13.30-17.15

P57

 

RNA isolation and EtOH purification

Haenen/Lange

Thu 12-04

13.30-17.15

P57

 

cDNA synthesis

Haenen/Lange

Fri 13-04

13.30-17.15

P57

 

Real time PCR

Haenen/Lange

 

 

 

 

Week 6 (Applications of Nutrigenomics)

 

Mon 16-04

13.30 – 17.15

PC612

 

Paper presentations

Lange/Müller

Tue 17-04

13.30-15.15

C8

NGG13

Paper presentations / Q & Answers

Müller

Wed 18-04

15.30-17.15

C8

NGG14

Examples of actual nutrigenomics projects;
Scientists (PhD students, postdocs) present their projects

3 PhD/PDs students
(IJssennagger, Stienstra, Georgiadi)

Thu 19-04

14.30-16.15

PC612

NGG15

Nutritional Systems Biology & Nutritional Science 2.0

Müller

 

 

 

 

Week 7 Study week

 

 

 

 

 

Week 8 Exam

 

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