|
Date |
Time |
Location |
Lecture |
Activity |
Lecturer |
|
|
|
|
|
Week 1 (What is the
problem?) |
|
|
Mon 7-3 |
13.30-17.15 |
PC713, PC717 |
|
eLearning
Case I/1
(Intro M. Müller) |
|
|
Tue 8-3 |
13.30-15.15 |
C8 |
NGG1 |
Concept &
Objectives of the Course
What is Nutrigenomics & molecular nutrition research? |
Müller |
|
Wed 9-3 |
15.30-18.00 |
C8 |
NGG2 |
Genomics
1: Overview / From Genotype to Phenotype
How to measure the nutritional phenotype? |
Müller |
|
Thu 10-3 |
13.30-17.15 |
C8 |
NGG3 |
Genomics
2: Genomics & Transcriptomics |
Müller |
|
Fri 11-3 |
13.30-17.15 |
|
|
Group work, Paper assignments |
|
|
|
|
|
|
Week 2 (What are the
tools?) |
|
|
Mon 14-3 |
13.30-17.15 |
PC713, PC717
|
|
eLearning
Case I/2 |
|
|
Tue 15-3 |
13.30-15.15 |
C8 |
NGG4 |
Genomics
3: Proteomics & Metabolomics / Applications of model systems |
Müller |
|
Wed 16-3 |
15.30-18.00 |
C8 |
NGG5 |
Nutrient
Sensing: The role of Sensing Transcription factors and Dietary Signaling
Routes |
Müller |
|
Thu 17-3 |
13.30-15.15 |
C8 |
NGG6 |
Nutrient
Sensing in organs / Role of intestine, liver, adipose tissue and PBMCs |
Müller |
|
Fri 18-3 |
13.30-17.15 |
|
|
Group work, Paper assignments |
|
|
|
|
|
|
Week 3 (From Genotype
to Phenotype) |
|
|
Mon 21-3 |
13.30-17.15 |
PC713, PC717 |
|
eLearning
Case II/1 |
|
|
Tue 22-3 |
13.30-15.15 |
C8 |
NGG7 |
Nutrition, Genetics and Sensitizing Genotypes |
Müller |
|
Wed 23-3 |
15.30-18.00 |
C8 |
NGG8 |
Complex
diseases: GWAS |
Müller |
|
Thu 24-3 |
13.30-15.15 |
C8 |
NGG9 |
Complex
diseases: From Genotype to Phenotype |
Müller |
|
Fri 25-3 |
13.30-17.15 |
|
|
Group work, Paper assignments |
|
|
|
|
|
|
Week 4 (From Health
to Diseases) |
|
|
Mon 28-3 |
13.30-17.15 |
PC713, PC717
|
|
eLearning
Case II/2 |
|
|
Tue 29-3 |
13.30-15.15 |
C8 |
NGG10 |
Epigenetics
and nutritional epigenomics |
Müller |
|
Wed 30-3 |
15.30-18.00 |
C8 |
NGG11 |
The role of
the intestine as gatekeeper (Host, microbes, foods) |
Müller |
|
Thu 31-3 |
13.30-15.15 |
C8 |
NGG12 |
The Role
of inflammation in the pathophysiology of complex diseases |
Müller |
|
Fri 1-4 |
13.30-17.15 |
|
|
Group work proposal / Paper assignments |
|
|
|
|
|
|
Week 5 (Practical
Part Dry Lab) Group A |
|
|
Mon 4-4 |
13.30-17.15 |
PC713, PC717
|
|
The Nutrigenomics Data Set |
Afman |
|
Tue 5-4 |
13.30-17.15 |
PC22 |
|
The Analysis |
Afman |
|
Wed 6-4 |
13.30-17.15 |
PC22 |
|
Data Mining 1 |
Afman |
|
Thu 7-4 |
13.30-17.15 |
PC21, PC411, PC610 (Forum) |
|
Data Mining 2 / Pathway Reconstruction |
Afman |
|
Fri
8-4 |
|
|
|
Goede Vrijdag (holiday) |
|
|
|
|
|
|
Week 5 (Practical
Part Wet Lab) Group B |
|
|
Mon 4-4 |
13.30-17.15 |
P57 |
|
Introduction practical course / Tissue culture (in groups) |
|
|
Tue 5-4 |
13.30-17.15 |
P57 |
|
RNA
isolation and EtOH purification |
|
|
Wed 6-4 |
13.30-17.15 |
P57 |
|
cDNA synthesis |
|
|
Thu 7-4 |
13.30-17.15 |
P57 |
|
Real time PCR |
|
|
Fri 8-4 |
|
|
|
Goede Vrijdag (holiday) |
|
|
|
|
|
|
Week 6 (Applications
of Nutrigenomics) |
|
|
Mon 11-4 |
|
|
|
|
|
|
Tue 12-4 |
13.30-15.15 |
C8 |
NGG13 |
Nutritional Systems Biology & Nutritional Science 2.0 |
Müller |
|
Wed 13-4 |
13.30-17.15 |
C8 |
NGG14 |
Examples
of actual nutrigenomics projects; PhD students present their projects |
PhD students, Hooiveld |
|
Thu 14-4 |
|
C8 |
NGG15 |
The role
of the food industry: Functional Foods, EFSA & Health Claims |
Witkamp |
|
|
|
|
|
|
|
|
Tue 14-4 –Fri 17-4 |
|
|
|
Week 7 Study week |
|
|
Fri 24-4 |
|
|
|
Week 8 Exam |
|
