Nutrition, Metabolism
& Genomics Group |
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Nutrition, Metabolism
& Genomics Group |
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The Nutrition, Metabolism and
Genomics Group (Nutrigenomics Group) focuses on
the nutritional regulation of metabolic pathways by nutrient sensing nuclear receptors
such as PPARs at the level of cells
and organs.
Currently, the nutrigenomics group is working on the regulatory effects
of fatty acids and other nutrients on gene expression, metabolic and regulatory
pathways and the functional implications of such regulation for
homeostasis. Particular attention is given to how disturbances in these
aspects specifically by the interaction with organ macrophages contribute to
local and systemic inflammation and ultimately to the development of the metabolic syndrome and
related diseases. Education is offered at BSc, MSc and PhD level on metabolic and physiological mechanisms underlying the effects of nutrition on metabolism, integration and coordination of nutrient metabolism, and nutrigenomics and nutritional systems biology. The focus of the training programs is on the use of molecular biology tools in nutrition research. Expertise and facilities include high-density microarray analysis (Affymetrix core lab) for whole genome gene expression analysis, large scale microarray database MADMAX and state-of-the-art bioinformatics and data mining tools (Ingenuity PA, Genomatix and Metacore), a broad range of molecular biology tools and animal models including various transgenic mice. |
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Eten volgens
je genenpakket (Voeding Nu april 2008) |
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Recent papers (more): |
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Address: |
Prof. dr. Michael Müller |
| former webpage version | |
